{"id":76439,"date":"2022-11-16T21:38:23","date_gmt":"2022-11-16T20:38:23","guid":{"rendered":"http:\/\/histocell.com\/cell-therapy-and-biologic-medicinal-products\/"},"modified":"2023-11-24T13:33:35","modified_gmt":"2023-11-24T12:33:35","slug":"cellular-and-biological-therapy-drugs","status":"publish","type":"page","link":"https:\/\/histocell.com\/en\/cellular-and-biological-therapy-drugs\/","title":{"rendered":"Cell Therapy and Biologic Medicinal Products"},"content":{"rendered":"\t\t
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\n\t\t\t\t\t<\/span>CELL THERAPY<\/span><\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Cell Therapy and Biologic Medicinal Products<\/span><\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\"c\u00e9lulahc\"\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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Cell-based drugs for human use.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Drugs for human use
based on substances secreted by the cells.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Cell Therapy <\/span>Programs<\/span><\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"terapia-celular\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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Our experience with adult mesenchymal stem cells<\/span><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t<\/span>Stem cells<\/span><\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Most basal mesenchymal stem cells die immediately after transplantation, limiting their therapeutic potential.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t<\/span>Oxidative stress<\/span><\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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During the acute phase of the disease, tissue is exposed to a highly damaging environment, with persistent oxidative stress and pathological inflammation.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\tINNOVATIVE CELL THERAPY PLATFORM<\/span><\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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HC016 Cells<\/span><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\tPROPRIETARY INNOVATION\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t
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  • New allogeneic adult mesenchymal stem cell technology for oxidative stress-mediated pathologies.<\/li>\n
  • Cells obtained from adipose tissue under a process patented by Histocell.<\/li>\n
  • Higher survival and bioactivity than basal mesenchymal cells in oxidative and inflammatory environments: proven increase in therapeutic efficacy.<\/li>\n<\/ul>\n

    Indications:<\/b><\/p>\n

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    • Pathologies associated with a highly oxidative microenvironment are particularly suitable targets for HC016 cells.<\/li>\n
    • Treatment of diseases with a relevant inflammatory component.<\/li>\n<\/ul>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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      \n\t\t\t\t\t\t\t\tRATIONALE\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t
      <\/p>\n

      \"\"<\/p>\n

      Enhanced therapeutic effect of mesenchymal stem cells (HC016), increasing <\/b>anti-inflammatory and antioxidant<\/b> response.<\/p>\n

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      • HC016 is configured to act in pro-inflammatory environments and aims to protect damaged host tissues.<\/li>\n
      • HC016 cells activate self-defence pathways against oxidative stress and inflammatory environments.<\/li>\n<\/ul>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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        \n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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        <\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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        \n\t\t\t\t\tCELL THERAPY<\/span><\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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        ASC cell-based therapeutic programmes<\/span><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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        \n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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        \t\t\t\t\t\t\t\t\t\t\t\t\"Man\t\t\t\t\t\t\t\t\t\t\t

        Treatment of acute spinal cord injuries.<\/p>\n

        Mesenchymal stem cells from adipose tissue patented by Histocell.<\/p>\n

        Phase I-IIa completed with 20 patients treated.<\/p>\n<\/div>HC016 Spinal cord<\/span><\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>

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        \t\t\t\t\t\t\t\t\t\t\t\t\"3D\t\t\t\t\t\t\t\t\t\t\t

        Treatment of acute respiratory distress syndrome (ARDS).<\/p>\n

        Mesenchymal stem cells from adipose tissue patented by Histocell.<\/p>\n

        Phase I-IIa completed with 26 patients treated.<\/p>\n<\/div>HC016 Lung disease<\/span><\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>

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        \t\t\t\t\t\t\t\t\t\t\t\t\"fracture\t\t\t\t\t\t\t\t\t\t\t

        Bone regeneration in non-union fractures, infections, resections, trauma.<\/p>\n

        Pre-differentiated ASCs.<\/p>\n

        Phase IIa completed with 12 patients with highly positive safety and efficacy results.<\/p>\n<\/div>bonecure<\/span><\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t

        <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

        CELL THERAPY Cell Therapy and Biologic Medicinal Products Cell-based drugs for human use. Drugs for human use based on substances secreted by the cells. Cell Therapy Programs Our experience with adult mesenchymal stem cells Stem cells Most basal mesenchymal stem cells die immediately after transplantation, limiting their therapeutic potential. Oxidative stress During the acute phase […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-76439","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/histocell.com\/en\/wp-json\/wp\/v2\/pages\/76439","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/histocell.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/histocell.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/histocell.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/histocell.com\/en\/wp-json\/wp\/v2\/comments?post=76439"}],"version-history":[{"count":4,"href":"https:\/\/histocell.com\/en\/wp-json\/wp\/v2\/pages\/76439\/revisions"}],"predecessor-version":[{"id":77728,"href":"https:\/\/histocell.com\/en\/wp-json\/wp\/v2\/pages\/76439\/revisions\/77728"}],"wp:attachment":[{"href":"https:\/\/histocell.com\/en\/wp-json\/wp\/v2\/media?parent=76439"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}