Dermo-cosmetics administrador 15/11/2022
DERMO-COSMETICS

Active ingredients, medical devices and cosmetic products

Development and manufacture of effective products of natural origin for dermo-cosmetic skin and hair treatments.

Histocell presents as an ideal partner for open innovation in dermo-cosmetics.

Specialists in biotechnologies focused on regeneration and oxidative stress control applied to dermo-cosmetics.

cuidado-piel
OUR KNOW-HOW
Biotechnologies
Histocell has two proprietary technologies
HISTOESSENCE

Technology based on a unique natural blend of sulphated glycosaminoglycans (chondroitin sulphate, heparan sulphate, keratan sulphate and dermatan sulphate) and polydisperse hyaluronic acid.

What do these components bring?

  • Recreates and regenerates the extracellular matrix
  • Induces synthesis of collagen and fibronectin
  • Promotes cell migration

HISTOESSENCE MIMICS THE EXTRACELLULAR MATRIX

Self-controlled industrial purification process providing extracellular matrix at different purities for a family of products (cosmetics - class III medical devices).

REOXDERM

Technology based on an exclusive blend of natural antioxidant active ingredients.

What do these components bring?

  • LBG (galactomannan): obtained from carob seed flour. Used in traditional medicine as an antioxidant and anti-inflammatory solution.
  • Ascorbic acid: essential micronutrient for wound healing. Induces collagen synthesis and gives strength and resilience to new tissue.
  • Alpha-tocopherol: a natural antioxidant that reduces the formation of ROS and protects cell membranes.
  • Lycopene: carotene that neutralises ROS from oxidative stress. Oxidative cascade blocker.
  • Turmeric: source of vitamins and minerals. Prevents oxidation and provides defence against the inflammatory environment.

PREVENTS AND PROTECTS CELLULAR COMPONENTS FROM FREE RADICAL-INDUCED DAMAGE BY BOOSTING INTRACELLULAR DEFENCE MECHANISMS.

SHARPLY DECREASES INTRACELLULAR LEVELS OF ROS.

PRODUCTS ON THE MARKET
Active ingredients
WHARTON GEL COMPLEX

Cosmetic ingredient for dermo-cosmetics designed based on Histoessence technology.

REOXDERM

Cosmetic ingredient for dermo-cosmetics designed on the basis of Reoxcare technology.

PRODUCTS ON THE MARKET
Medical devices
HISTOESSENCE INJECTABLE

Sterile injectable mesotherapy solution designed based on Histoessence technology.

Natural glycosaminoglycans (15 mg/ml)

RESEARCH SERVICES FOR INNOVATIVE PRODUCTS
In vitro testing
CELL TYPES AND MODELS
  • Fibroblasts, keratinocytes, mesenchymal stem cells
  • Oxidative stress model
  • Senescence model
  • UV radiation exposure model
IN VITRO TESTING
  • Cell viability and behaviour
  • Protein immunolocalisation
  • Mitochondrial activity
  • Chemotactic effect
  • Antioxidant capacity and determination of intracellular ROS
  • Gene expression
  • Secretion of methyl-metalloproteases
  • Antimicrobial and antibiofilm effect
DEVELOPMENT AND MANUFACTURE OF PROFESSIONAL AND HOME-CARE PRODUCTS
Manufacturing for third parties

Cosmetic solutions for professional topical use: dermapen, microneedling, ...

Sterile medical devices for injectable use: mesotherapy, biorevitalisation, ...

Approved manufacturing facilities for medical devices and dermo-cosmetics 600 sqm

Production capacity from pilot batches to large industrial batches.